Variations within Class-A β-Lactamase Physiochemical Properties Reflect Evolutionary and Environmental Patterns, but not Antibiotic Specificity
Figure 8
The best-fit heat capacity curve by mDCM is shown with usol = −2.61, vnat = −0.32 and δnat = 1.61, which are within normal ranges established by our previous studies (solid line = model and symbols = experiment).
The three fitting parameters are required to calculate free energy of the protein accurately using Eq. 1.