Dynamic Fluctuations Provide the Basis of a Conformational Switch Mechanism in Apo Cyclic AMP Receptor Protein
Figure 3
Dynamics network of apo CRP monomer/dimer and holo CRP by MD simulations.
The correlation between residue fluctuations based on first ten essential modes is calculated as an average over three parallel MD runs for apo CRP monomer/dimer and holo CRP MD trajectories. The correlation maps are given for: (A) apo CRP monomer AVG, (B) apo CRP dimer AVG, and (C) holo CRP (single run).