Transcription Factor Binding Profiles Reveal Cyclic Expression of Human Protein-coding Genes and Non-coding RNAs
Figure 2
Regulator scores of TFs on genes can discriminate cell cycle (CC) versus non-cell cycle (non-CC) genes.
(A) Distributions of regulatory scores for CMYC and E2F1 are significantly different between CC and non-CC genes (P = 2e-55 and P = 1e-50, respectively). (B) The average signals of CMYC and E2F1 show similar distributions between CC and non-CC genes (P = 0.03 and P = 0.05, respectively) (C) The t-scores for CC versus non-CC genes calculated by comparing regulatory scores and average signals of TFs. SYDH, UTA and HAIB are the Lab IDs of a dataset.