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A Model for the Self-Organization of Vesicular Flux and Protein Distributions in the Golgi Apparatus

Figure 4

Steady state concentrations of three classes of enzymes in the unrestricted fusion scenario.

Golgi enzyme concentrations are normalized by their maximum value. The parameters are: Decay rates for the cis and trans t-SNARE are , the vesicular transport coefficient , and dissociation constants for vesicular binding are: for the ER v-SNARE, for the cis t- and v-SNAREs, for trans t-SNARE, for trans v-SNARE, for cis enzymes, for medial enzymes, and for trans enzymes. Initial concentrations of all proteins in the first cisterna are , and the concentration of the t-SNARE in the ER is 0.7.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1003125.g004