< Back to Article
A Model for the Self-Organization of Vesicular Flux and Protein Distributions in the Golgi Apparatus
Figure 3
Self-generated steady state distributions of alpha and beta SNAREs and enzymes as it is observed in the Golgi apparatus.
Panel A: 
t-SNARE (solid line) and v-SNARE (circles) coinciding with t-SNARE, and 
t-SNARE (dashed line) and v-SNARE (dotted line) vs. the cisternal number 
. Panel B: cis (solid line), medial (dashed line) and trans (dotted line) Golgi enzymes normalized by their maximum value vs number of cisterna 
. The parameters are: Decay rates 
are zero for all substances except for 
t-SNARE for which 
, the vesicular transport coefficient 
, and dissociation constants for vesicular binding are 
for ER v-SNARE, 
for cis t- and v-SNAREs, 
for trans t-SNARE, 
for trans v-SNARE, 
for cis enzymes, 
for median enzymes, and 
for trans enzymes. Initial concentrations of all substances in the first cisterna are 
, and the concentration of t-SNARE in ER is 0.7.
doi: https://doi.org/10.1371/journal.pcbi.1003125.g003