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Shared Protein Complex Subunits Contribute to Explaining Disrupted Co-occurrence

Figure 1

Visualization of complementarity score and illustration of triangle types.

(A) Constitution of the two TOR sub-complexes TORC1 and TORC2 complex. (B) Phylogenetic profiles (as an example) of TOR and Rptor and Rictor and the formed triangle. The nodes represent proteins and the lines indicate a pairwise interaction. (C) Visualization of the complementary score and the different triangle types used throughout the study. We consider “open” and “closed” triangles and closed triangles with 2 inparalogs. The ellipses symbolize the different complexes.

Figure 1

doi: https://doi.org/10.1371/journal.pcbi.1003124.g001