Leveraging Prior Information to Detect Causal Variants via Multi-Variant Regression
Figure 2
Distributions of three informative weights (r, phastCons and r×phastCons) for causal variants and non-causal variants on the causal and null chromosomes in the simulation study.
In each MAF range, weights were collected from 200 replicates, and weights in each replicate were scaled by dividing each by the maximal value so as to bound final weight between 0 and 1.