Scrutinizing MHC-I Binding Peptides and Their Limits of Variation
Figure 4
Architecture of the best-performing cascaded machine-learning model based on six first stage classifiers originating from three differing descriptor sets and two learning schemes (ANNs, SVMs) and a jury neural network containing three hidden neurons.
The model delivers a prediction score from the interval [0,1[, with high values indicating MHC-I H-2Kb binding.