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Scrutinizing MHC-I Binding Peptides and Their Limits of Variation

Figure 3

Workflow for the development of the cascaded machine-learning model.

ANN: feed-forward artificial neural network, SVM: support vector machine. AAFREQ, BINAATYPE, BINPEP, PEPCATS, PPCA and PPCALI correspond to the utilized peptide descriptors (cf. Methods). TP, FP, FN and TN correspond to entities of a confusion table with true-positives, false-positives, false-negatives and true-negatives.

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1003088.g003