Scrutinizing MHC-I Binding Peptides and Their Limits of Variation
Figure 2
The Immune Epitope Database (IEDB) served as data source [14]. The murine H-2Kb allele and a length of eight were selected due to good data availability and reference model character. The core set exhibits similar contributions of positive (636) and negative (526) examples, while redundant ambiguous entries were removed. The core set contained binders and non-binders partially, fully and not agreeing with the canonical sequence motif.