Inference of Gene Regulatory Networks with Sparse Structural Equation Models Exploiting Genetic Perturbations
Figure 6
The network of 39 human genes inferred from gene expression and eQTL data with the SML algorithm.
The 39 genes related to the immune function were chosen from [45] to have a reliable eQTL per gene. The SML algorithm was run with stability selection and edges were detected at an . See Table 3 for the IDs and description of 39 genes. IGH in this figure corresponds to gene ID ENSG00000211897. A
edge stands for inhibitory effect and a
edge stands for activating effect.