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A Balance Equation Determines a Switch in Neuronal Excitability

Figure 10

Joint variations of the inactivation gates of -type calcium channels and resurgent sodium channels induce excitability switches in cerebellar granule cells.

A. Two parameter bifurcation diagram of the mode with and as bifurcation parameters. TC denotes a branch of transcritical bifurcations detected following the algorithm in Table 2. B. Electrophysiological responses of the model to step inputs of excitatory/inhibitory current: left , right .

Figure 10

doi: https://doi.org/10.1371/journal.pcbi.1003040.g010