A Multi-scale Analysis of Influenza A Virus Fitness Trade-offs due to Temperature-dependent Virus Persistence
Figure 7
Virus decay rate at different temperatures.
A) environmental, between-host temperature, , and B) within-host temperature,
, as a function of
(decay rate at 0 degrees Celsius). Solid lines are theoretical values obtained by choosing a value of
and computing the corresponding value for
from the regression equation
, where the values for
and
are the best-fit values obtained previously by fitting the decay data for the different strains. The dashed horizontal line indicates the level of
above which within-host fitness is so small that no infection takes place. H5N2 is highlighted as a strain with poor persistence at both low and high temperatures – see text.