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A Multi-scale Analysis of Influenza A Virus Fitness Trade-offs due to Temperature-dependent Virus Persistence

Figure 1

Flow diagram for the within-host model.

, , and are the variables describing uninfected cells, infected cells, and infectious virus. Uninfected cells become infected at rate , infected cells produce virus at rate and die at rate . Virus decays at rate . Solid lines indicate physical flows, dashed lines indicate interactions.

Figure 1

doi: https://doi.org/10.1371/journal.pcbi.1002989.g001