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Processing of Multi-dimensional Sensorimotor Information in the Spinal and Cerebellar Neuronal Circuitry: A New Hypothesis

Figure 1

The information provided by the spinocerebellar and spinoreticulocerebellar mossy fibers derives from the spinal interneuron circuitry.

The vermis and pars intermedia of the cerebellum receives a substantial part of their mossy fiber inputs from the SCT/SRCT pathways [19]. The SCT/SRCT pathways consist of spinal interneuron projections either directly as mossy fibers (rostral spinocerebellar tract, RSCT), via a relay in the lateral reticular nucleus of the brainstem (spino-reticulo cerebellar path, SRCT), or via relay cells located in the spinal cord (ventral and dorsal spinocerebellar tracts, VSCT and DSCT) [19]. These spinal interneurons can project directly to alpha-motorneurons and likely form an integral part of the spinal motor circuitry, by conveying sensory feedback and motor commands to the motor nuclei of the spinal cord [99].

Figure 1

doi: https://doi.org/10.1371/journal.pcbi.1002979.g001