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Directional Summation in Non-direction Selective Retinal Ganglion Cells

Figure 11

Directional summation in a simple model system.

A) A cell with an unbranched dendrite was activated at multiple locations to elicit summed EPSPs. B) EPSPs for a model without dendritic voltage-dependent channels as measured at the soma. C) EPSPs after dendritic HCN channels have been added. D) EPSPs after Na/K channels were added to the model. E) EPSPS from a model with Na/K/HCN channels. F) A plot of the % direction selectivity (DS; [away-toward]/toward*100) for amplitude and charge in each condition from B–E.

Figure 11

doi: https://doi.org/10.1371/journal.pcbi.1002969.g011