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Directional Summation in Non-direction Selective Retinal Ganglion Cells

Figure 10

HCN channels confer centrifugal directionality to summation.

A) Summed EPSPs (average of 8 trials) before and after ZD7288 application. B) Plots of the charge ratio (summed depolarization/sum of individual depolarization charges) after application of ZD7288. There was no significant difference in the charge ratio after blockade of HCN (paired t-test, p>0.05; N = 8 cells). C) A plot of the change in the charge ratio after channel block.

Figure 10

doi: https://doi.org/10.1371/journal.pcbi.1002969.g010