Directional Summation in Non-direction Selective Retinal Ganglion Cells
Figure 8
Blockade of HCN channels increases distal EPSP size.
A) Traces (average of 8 trials) for proximal and distal locations before and after application of ZD7288 (100 µM) to block HCN channels. B) A plot of the increase in charge in both directions after ZD7288 application. C) Summation ratio for three uncaging pulses to the locations in A, with ZD7288 in the bath (*ANOVA; p<.05; N = 8 cells).