Directional Summation in Non-direction Selective Retinal Ganglion Cells
Figure 2
Dendritic summation is supralinear in retinal ganglion cells.
A) A confocal image of an On ganglion cell filled with Oregon green-BAPTA (100 µM). Trains of 3 uncagings were delivered to an individual location (arrow) at varying intervals (1–125 ms). Lower left trace is the light response, bar indicates light duration. B) Summed depolarization uncaging responses (traces are averages of 8 trials). C) A plot of the total charge for summed depolarizations/sum of 3 individual depolarization charges for locations <50 µm from the soma. D) Locations >125 µm from the soma. E) Pooled data (ANOVA p<0.001; N = 11 On cells).