RFECS: A Random-Forest Based Algorithm for Enhancer Identification from Chromatin State
Figure 6
Enhancer predictions in ENCODE cell-lines using RFECS.
A.)Validation Rate in the 12 cell-types measured by overlap with DNase-I HS, B.)Misclassification Rate in the cell-types measured as overlap of UCSC TSS, C.)Average false discovery rate (FDR) over the 22 autosomal chromosomes for each cell-type plotted as a function of voting percentage of trees, D.)Validation rate and misclassification rate for each cell-type at a FDR of 5% with number of enhancer predictions shown above the bar.