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Differential Expression Analysis for Pathways

Figure 5

Power curve, variable gene variance.

Performance of GSEA, SPIA, and DEAP are compared as gene variance (σ2g) changes. Power (y-axis) is the ratio of simulations, out of 5000 (5 pathways, 1000 simulations each), which were identified as significant (p<0.05). Constants were μ = 0.5 and sample size = 10.

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1002967.g005