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Differential Expression Analysis for Pathways

Figure 3

Simulated pathways.

Five pathways designed to test analysis approaches are illustrated. Nodes labelled in green and red were built around distributions with μ of +X and −X, respectively, where X represents a numerical value. Gray nodes represent data sampled from the standard normal distribution. Edges with arrows and bars represent catalytic and inhibitory relationships, respectively.

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1002967.g003