Computational Biomarker Pipeline from Discovery to Clinical Implementation: Plasma Proteomic Biomarkers for Cardiac Transplantation
Figure 2
Average Linear Discriminant Analysis classifier score (Classifier score) for all available acute rejection (AR) samples (pink solid point), and non-rejection (NR) samples from NR patients (green solid triangle), at each time point. The score was centered at the LDA cut-off point so that samples with positive and negative scores are classified as “rejection” or “non-rejection”, respectively. Vertical lines represent standard errors. Means and standard error bars can be used to assess differences of the score between groups at any of the studied time points. Sample sizes available at each time point are shown in the bottom table.