Chapter 15: Disease Gene Prioritization
Figure 4
PolySearch gene-disease associations.
PolySearch uses PubMed lookup results to prioritize diseases associated with a given gene. Here, screen shots of the top two results (where available; sorted by relevancy score metric) from PolySearch are shown. According to these, BRCA1 and PIK3CA are associated with breast cancer, while MC4R and CLC1 are not. These results quantitatively confirm intuitive inferences made from simple PubMed searches.