Chapter 15: Disease Gene Prioritization
Figure 2
MC4R-centered protein-protein interaction network.
The figure illustrates protein-protein interaction neighborhood of the human melanocortin 4 receptor (MC4R) as illustrated by the confidence view of the STRING 8.3 server. The nodes of the graph represent human proteins and the connections illustrate their known or predicted, direct and indirect interactions. The connection between any two protein-nodes is based on the available information mined from relevant databases and literature. The network includes all protein interactions that have >0.9 estimated probability.