Binding of Nucleoid-Associated Protein Fis to DNA Is Regulated by DNA Breathing Dynamics
Figure 2
DNA local breathing dynamics of FIS1 and FIS2.
The nucleotide positions are shown along the horizontal axis. Positions corresponding to points-of-contact are highlighted in yellow while the bubble formation region is highlighted in blue. The length of the transient bubbles (in number of base pairs [bp]) is shown along the vertical axis. The color map represents the probability for bubble openings where the red color denotes high probability and blue color denotes low probability. The name of the sequence for each variant is shown in the panel (all sequences can be found in Table 1).