Integrating Phylodynamics and Epidemiology to Estimate Transmission Diversity in Viral Epidemics
Figure 3
Contour plots showing how generation time (T), basic reproductive number (R0) and the proportion of transmitters in the population (u) co-vary.
Gray bands highlight different values of u. The area between the white dashed lines represents R0 values estimated by sensitivity analysis of mortality and recovery rate (Table S3). The area between the yellow dashed lines represents the 95% confidence limits of R0 values estimated assuming 40 years of infectivity and 70 years of life expectancy. The black dots show the maximum T value for each subtype, which is defined by empirical values for u and the median values of R0 (see text).