Ribosome Traffic on mRNAs Maps to Gene Ontology: Genome-wide Quantification of Translation Initiation Rates and Polysome Size Regulation

doi:10.1371/journal.pcbi.1002866

Ribosome Traffic on mRNAs Maps to Gene Ontology: Genome-wide Quantification of Translation Initiation Rates and Polysome Size Regulation

Figure 7

Scatter plots of different estimators of protein production rates.

(A) versus abundance of proteins. The mRNA abundances are from [30] and the experimentally measured protein levels from [51]. The plot shows a clear correlation between the model prediction of the amount of proteins in the cell and the experimental values. (B) CAI from [30] versus protein abundance. (C) and (D) show different variants of the tRNA adaptation index, tAIc and tAIp from [30], vs protein abundance. Our approach yields a better correlation between the predicted and measured protein abundance.

doi: https://doi.org/10.1371/journal.pcbi.1002866.g007