The Underlying Molecular and Network Level Mechanisms in the Evolution of Robustness in Gene Regulatory Networks
Figure 3
Evolution of robustness depends on URR length and specificity gap.
(A) Change in robustness, measured as the difference of the mean phenotypic distances between unperturbed and perturbed individuals at generations 2000 and 0. The mutation rate used for this measure was 1 mutation per 100 bp per genome. (B) Change in connectivity (comparing generation 2000 to generation 0), measured by the fraction of unique inputs in the network of a given individual. The numbers at the end of each bar represent the connectivity at the end of the simulations. Error bars are the standard error of the mean over 100 independent simulations.