ADEMA: An Algorithm to Determine Expected Metabolite Level Alterations Using Mutual Information
Figure 11
Predicted Metabolite Levels for the In Silico Dataset.
This figure depicts the simplified Glycolysis pathway as described by the BioModels model Wolf2000_Glycolytic_Oscillations. Figure shares the legend of Figure 7. As the variable group has increased Glucose levels, and, therefore, increased input to the model, the expectation is to observe an increase in the overall metabolite levels. As expected ADEMA predicts that every single metabolite is increased in the variable group, with respect to the control group.