Calcium Wave Propagation in Networks of Endothelial Cells: Model-based Theoretical and Experimental Study
Figure 12
Experiment image and normalized intensity of cells in “T” structure subjected to double stimulation.
(A) Image of a T structure of cells subjected to double mechano-stimulation. The red circle identifies the stimulated cells. Red labels indicate the response time individual cells. All the cells exhibited strong fluorescence with response times calculated from the rate of change of the fluorescence intensity. Black labels show cells exhibiting only noise level fluorescence. (B–E) show the normalized intensity of fluorescence of branch 1, cluster area, branch 2 and branch 3, respectively, as functions of time. The vertical axis is the dimensionless normalized intensity of fluorescence and the horizontal axis is the time in seconds in intervals of 1.2 s between recordings.