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Calcium Wave Propagation in Networks of Endothelial Cells: Model-based Theoretical and Experimental Study

Figure 5

Simulated calcium concentration for cells in a single chain subjected to a single stimulus.

We label the stimulated cell 4 (cell 31 in the chain of 61 cells). We report the response of cells on either side of the stimulated cell as cell 5 through cell 9 and cell 1-through cell 3 to facilitate comparison with experimental results. The real time is obtained by scaling the cell-to-cell propagation time of the simulation to that of the experiment (see text for details).

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1002847.g005