Calcium Wave Propagation in Networks of Endothelial Cells: Model-based Theoretical and Experimental Study
Figure 4
Experiment image and normalized intensity of cells in single fine line subjected to single stimulus.
(A) Image of a finite single fine line of cells. Cells are labeled 1 through 9. The stimulating probe is clearly visible on the right of the stimulated cell (cell 4 labeled with a red circle). The time (in sec) at which the normalized fluorescence reaches its maximum positive rate of change is indicated for every cell. The uncertainty for each one of these times is 0.6 s. The origin of time is the time at which fluorescence in the stimulated cell attains its maximum rate of change. (B) and (C) show the normalized intensity of fluorescence of cells 4 through 9 and cells 3 through 1, respectively, as functions of time. The vertical axis is the dimensionless normalized intensity of fluorescence and the horizontal axis is the time in seconds in intervals of 1.2 s between recordings.