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Nucleoid-Associated Proteins Affect Mutation Dynamics in E. coli in a Growth Phase-Specific Manner

Figure 4

Mutability at 5-methylcytosine deamination hotspots.

C∶G to T∶A mutability at the second cytosine in CCWGG motifs and CCWHH control motifs (expressed as changes per context at risk) for sequence bound by a specific NAP (either H-NS, IhfA, or IhfB) either exclusively early (light green) or exclusively late (dark green) or never (blue) bound by any of the NAPs considered (including Fis).

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1002846.g004