Chapter 9: Analyses Using Disease Ontologies
Figure 6
Disease terms significantly enriched in annotations of aging-related genes: The tag cloud shows those disease terms in the annotations of the 261 aging related genes that are statistically enriched given our gene–disease background annotation dataset.
Terms that are significantly enriched appear larger. We used a binomial test to detect enriched disease terms in the aging related gene set. Note that mis-annotated terms (such as Recruitment) and non-informative terms (such as Disease) are not deemed enriched by the statistical analysis.