Chapter 13: Mining Electronic Health Records in the Genomics Era
Figure 4
Use of NLP to identify patients without heart disease for a genome-wide analysis of normal cardiac conduction.
Using simple text searching, 1564 patients would have been eliminated unnecessarily due to negated terms, family medical history of heart disease, or low dose medication use that would not affect measurements on the electrocardiogram. Use of NLP improves recall of these cases without sacrificing positive predictive value. The final case cohort represented the patients used for GWAS in [71].