Temporal Expression-based Analysis of Metabolism
Figure 4
Sensitivity analysis for Type 2 gene-specific threshold.
(A) Total carbon concentration in media for each penalty threshold θ, summed over all time points. Penalty thresholds between 40% and 75% exhibit enrichment for intermediate carbon sources formate, glycolate, pyruvate. (B) Extinction time of lactate and ammonium in the media. Lactate runs out significantly earlier for intermediate penalty thresholds. Heatmap indicates the total media concentration of secreted carbon sources (acetate, pyruvate, glycolate, formate).