Functional Analysis of Metabolic Channeling and Regulation in Lignin Biosynthesis: A Computational Approach
Figure 2
Scaffold of topological configurations.
The relevant metabolites and enzymatic reactions (arrows) for the biosynthesis of guaiacyl (G), 5-hydroxyguaiacyl (5HG), and syringyl (S) lignin monomers are shown in black, if they are included in all topological configurations, or gray, if they are included in only some specific configurations. G and S channels are represented as blue and red arrows, respectively. Notice that 5-hydroxyconiferyl alcohol is allowed to be incorporated into lignin polymer as 5HG subunit because this actually occurs when COMT is down-regulated [41]. Enzymes are highlighted in bold and italics.