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A Graphical Modelling Approach to the Dissection of Highly Correlated Transcription Factor Binding Site Profiles

Figure 6

DDGraphs for the 5 CRM classes inferred by the NCPC algorithm at α = 0.05.

Variables in green circles are target variables. Variables in ovals are inferred causal neighbours. Variables in rectangles are inferred to have indirect dependence with the target. Values on the edges are (unadjusted) P-values from conditional independence tests. The same NCPC algorithm with no multiple testing correction was used as in the synthetic data benchmark. See Figure 1 for the graphical vocabulary.

Figure 6

doi: https://doi.org/10.1371/journal.pcbi.1002725.g006