Modeling Dynamic Regulatory Processes in Stroke
Figure 8
Comparison between neuroprotected and injurious networks.
Clusters containing more than 5 genes are shown (green squares) as determined by our functional clustering approach. The influences between clusters are shown as directed edges with red arrows indicating a positive influence (activation) and blue T lines indicating a negative influence (repression). Dashed lines indicate relationships that are significantly different between injurious and non-injurious conditions, either absent in one or opposite sign. General functional categories chosen from statistically enriched functions are indicated in grey boxes.