This Déjà Vu Feeling—Analysis of Multidomain Protein Evolution in Eukaryotic Genomes
Figure 4
Clade-specific domains and domain combinations.
This figure shows the numbers of clade-specific domain combinations (black numbers after the slash) and core domain combinations (black numbers before the slash) for select clades. Below these are the numbers of clade-specific domains (gray numbers after the slash) and core domains (gray numbers before the slash). Numbers in brackets refer to domain combination counts under exclusion of the amphioxus Branchiostoma floridae genome. The numbers of analyzed genomes are shown in parentheses below the clade names. For example, the 19 analyzed vertebrate genomes contain 1,416 clade-specific domain combinations, 102 of which are found in each of the 19 analyzed genomes. These 19 genomes also contain 380 clade-specific domains, out of which 67 are present in each vertebrate genome. Ambulacraria is a clade of deuterostomes that includes echinoderms and hemichordates. To facilitate comparison of different taxonomic levels, established phyla are shown with a light-blue background, whereas super-phyla have a light-purple background. This figure was made using the “gathering” cutoffs provided by Pfam. For a detailed description of parameters, see Materials and Methods. Complete counts are shown in Table S6.