Quantitative Predictions of Binding Free Energy Changes in Drug-Resistant Influenza Neuraminidase
Figure 3
Comparison of WT and mutant dynamics.
For WT and H274Y, N294S, and Y252H, distance distributions between the atoms Cδ of E276 and Nε of R292 and between the atoms Cδ of E277 and Nε of R292 are shown for oseltamivir (A, C) and zanamivir (B, D), respectively.