Spontaneous Excitation Patterns Computed for Axons with Injury-like Impairments of Sodium Channels and Na/K Pumps
Figure 9
Increased Imaxpump shortens bursting periods (BP) and burst duration (BD).
(A)–(E) Five values of Imaxpump as labeled elicited activities as shown with LS: Gaussian distribution, 2.5±1 mV (steady-state values in the absence of CLS injury are listed in Table 2). Note the different time scales in each panel. For a bursting node, Ipump is periodic with a period equal to BP. Inset in (A) shows the effect of injecting a 12 µA/cm2 stimulating current. (F) For direct comparison of BPs and burst durations, Ipump traces from panels A–E (color coding preserved) are plotted together.