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Spontaneous Excitation Patterns Computed for Axons with Injury-like Impairments of Sodium Channels and Na/K Pumps

Figure 7

Noise induces or modifies bursting.

(A) Without noise, bursts are as shown in Figure 6B but here, under the influence of noise (σ = 0.1 µA/cm2), the bursting periods are random. Right (here and in B): an expanded section showing STOs induced by noise via coherence resonance. (B) Without noise the system is in the bistability regime as shown in Figure 6C, but here, noise (σ = 0.4 µA/cm2) causes Vm to randomly visit quiescent or repetitive firing states, hence producing noisy bursts.

Figure 7

doi: https://doi.org/10.1371/journal.pcbi.1002664.g007