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Diversity and Noise Effects in a Model of Homeostatic Regulation of the Sleep-Wake Cycle

Figure 3

Scheme of the heterogeneous model.

Example of model system with orexin-producing neurons , (red spheres) and one neuron B (blue sphere). The neurons A interact with each other through an all-to-all coupling (red lines). Blue and red projections have a meaning similar to those of Fig. 1: the neuron B is coupled to the neurons through parallel glutamate projections, while each neuron is coupled to neuron B through a glutamate and an orexin projection. The neurons A are also acted upon by a stimulus representing the effect of the circadian clock (gray arrows).

doi: https://doi.org/10.1371/journal.pcbi.1002650.g003