Gene Network Homology in Prokaryotes Using a Similarity Search Approach: Queries of Quorum Sensing Signal Transduction
Figure 7
Annotated 2D similarity plot for Lsr system LMNAST weak search hits.
A. HGT of homologous systems is evident among hits with perfect organizational homology but diminished mean element homology. A great number of hits have low similarity along both axes. As seen in B., these hits are mostly involved in the metabolism of 5 carbon carbohydrates according to their annotation. This is likely reflective of the fact that AI-2 is of similar structure to 5 carbon sugars.