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Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation

Figure 6

SNP expression distributions according to allelic imbalance direction.

SNPs in strong APA signal, with high GU level and high miRNA score, have a significantly higher logarithm of SNP expression for SNPs with imbalance towards APA allele (positive (P) log allelic ratio), compared to SNPs with imbalance towards non-APA allele (negative (N) log allelic ratio).

Figure 6

doi: https://doi.org/10.1371/journal.pcbi.1002621.g006