Genome-Wide Localization of Protein-DNA Binding and Histone Modification by a Bayesian Change-Point Method with ChIP-seq Data
Figure 2
The distance from H3K36me3 island boundaries to nearest gene boundary was used as a measure of accuracy.
H3K36me3 islands have been shown to correspond to actively transcribed gene bodies so we expected the boundaries of island and genes to coincide. The sum of the distances from both upstream and downstream island boundaries to the nearest gene boundaries were used as a per island error and illustrated in the histogram for BCP (left) and SICER (right).