Location-Dependent Excitatory Synaptic Interactions in Pyramidal Neuron Dendrites
Figure 3
Proximal-distal interactions: predictions of the detailed compartmental model.
A, Location pairs are indexed on outer x and y axes, and depicted by electrode icons in insets (number shown under electrodes is separation distance). Proximal and distal stimulus intensity is indexed on inner x and y axes, respectively, in each subplot. Striped lines in 3 subplots on main diagonal are shown in (B). B, Dendritic spike threshold and amplitude recorded at the soma increased markedly as electrodes approached soma. C, Superposition of curves normalized to first suprathreshold point shows nearly invariant basic shape of input-output curve. The normalization was a x,y-scaling of each curve such that the first suprathreshold data point was placed at the middle of the plot.