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Modeling Within-Host Dynamics of Influenza Virus Infection Including Immune Responses

Figure 5

Best fits of different models to experimental data.

Model 1 is described by Eq. (1). Model 2 is Eq. (1) with κ = 0, i.e., no killing of infected cells by NK cells. Model 3 is model 2 assuming the viral production rate is . The detection limit of the viral titer is 100 RNA copies per ml of nasal secretions. Data below the detection limit were plotted as 1 RNA copy per ml of nasal secretions.

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1002588.g005